//Parent class
namespace Framework.DataModel
{
    [Serializable]
    public class DataTreeRequest : TreeNode,IDirtyListener,ISerializable
    {
        ....
    }
}

// Derived Class    
namespace Framework.DataModel
{
    [Serializable]
    public class CADElementRequest : DataTreeRequest
    {
        public CADElementRequest(String name) : base(name){}
    }
}


// Method that uses reflection to create class and then cast to its base class
namespace Framework.DataModel
{
    [Serializable]
    public class DataModelBuilder : CoreBuilder
    {
        ...

        protected DataTreeRequest CreateDataTreeRequest(String asmName,String inName,String inType,String inSourceName)
        {
            DataTreeRequest dtr = null;

            Assembly asm = Assembly.LoadFrom(asmName);
            if (asm == null)
            {
                throw new BaseException("Can't find assembly " + asmName);
            }

            Type requestType = asm.GetType(inType);
            if (requestType == null)
            {
                throw new BaseException("Can't find class of type " + inType + " in assembly " + asmName);
            }

            // Call the constructor for the tree node that takes the xml node as an argument
            Type[] constructorArgsTypes = new Type[1];
            constructorArgsTypes[0] = typeof(String);
            ConstructorInfo constructorInfo = requestType.GetConstructor(constructorArgsTypes);
            if (constructorInfo == null)
            {
                throw new BaseException("Can't find constructor for type " + inType + " that takes a String param");
            }

            Object[] constructorArgs = new Object[1];
            constructorArgs[0] = inName;
            Object newObj = constructorInfo.Invoke(constructorArgs);

            // Code fails on this line trying to cast derived class to base class on 1 in 100 machines
            dtr = newObj as DataTreeRequest;
            if (dtr == null)
            {
                throw new BaseException("Can't cast newObj to type DataTreeRequest. newObj = " + newObj + ",Type = " + newObj.GetType().ToString());
            }

            dtr.InSource = inSourceName;

            return dtr;
        }
    }
}

在失败的机器上记录输出：

Message = Found assembly=Framework.DataModel,Version=1.0.5885.31486,
Culture=neutral,PublicKeyToken=null

Message = newObj
AssemblyQualifiedName=Framework.DataModel.CADElementRequest,
Framework.DataModel,Culture=neutral,
PublicKeyToken=null,BaseType==Framework.DataModel.DataTreeRequest,
FullName==Framework.DataModel.CADElementRequest

BaseException: Can’t cast newObj to type DataTreeRequest. newObj =
Name=Substations;InType=;InName=Substations;OutName=Substations;InSource=;OutSource=;,
Type = Framework.DataModel.CADElementRequest