>使用pip install comtypes

要么
>从https://pypi.python.org/pypi/comtypes下载然后解压缩下载文件夹.在解压缩的文件夹中找到setup.py.打开cmd转到setup.py的路径,然后运行命令python setup.py install

现在只需运行code.py文件,您可以通过更改函数SetMasterVolumeLevel(-25,None)的第一个参数来调整音量,第一个参数必须介于-65到0之间.
我在Windows 8中尝试过这段代码,希望它可以在Windows 7上运行.

请参阅最后一行代码以查找volume.SetMasterVolumeLevel(-25,None)并调整PC的音量

Code.py

from comtypes import *
import comtypes.client
from ctypes import POINTER
from ctypes.wintypes import DWORD,BOOL

MMDeviceApiLib = \
    GUID('{2FDAAFA3-7523-4F66-9957-9D5E7FE698F6}')
IID_IMMDevice = \
    GUID('{D666063F-1587-4E43-81F1-B948E807363F}')
IID_IMMDeviceEnumerator = \
    GUID('{A95664D2-9614-4F35-A746-DE8DB63617E6}')
CLSID_MMDeviceEnumerator = \
    GUID('{BCDE0395-E52F-467C-8E3D-C4579291692E}')
IID_IMMDeviceCollection = \
    GUID('{0BD7A1BE-7A1A-44DB-8397-CC5392387B5E}')
IID_IAudioEndpointVolume = \
    GUID('{5CDF2C82-841E-4546-9722-0CF74078229A}')

class IMMDeviceCollection(IUnknown):
    _iid_ = GUID('{0BD7A1BE-7A1A-44DB-8397-CC5392387B5E}')
    pass

class IAudioEndpointVolume(IUnknown):
    _iid_ = GUID('{5CDF2C82-841E-4546-9722-0CF74078229A}')
    _methods_ = [
        STDMETHOD(HRESULT,'RegisterControlChangeNotify',[]),STDMETHOD(HRESULT,'UnregisterControlChangeNotify','GetChannelCount',COMMETHOD([],HRESULT,'SetMasterVolumeLevel',(['in'],c_float,'fLevelDB'),POINTER(GUID),'pguidEventContext')
        ),'SetMasterVolumeLevelScalar','GetMasterVolumeLevel',(['out','retval'],POINTER(c_float),'pfLevelDB')
        ),'GetMasterVolumeLevelScalar','SetChannelVolumeLevel',DWORD,'nChannel'),'SetChannelVolumeLevelScalar','GetChannelVolumeLevel','GetChannelVolumeLevelScalar','SetMute',BOOL,'bMute'),'GetMute',POINTER(BOOL),'pbMute')
        ),'GetVolumeStepInfo','pnStep'),'pnStepCount'),),'VolumeStepUp','VolumeStepDown','QueryHardwareSupport',POINTER(DWORD),'pdwHardwareSupportMask')
        ),'GetVolumeRange','pfMin'),'pfMax'),'pfIncr')
        ),]

class IMMDevice(IUnknown):
    _iid_ = GUID('{D666063F-1587-4E43-81F1-B948E807363F}')
    _methods_ = [
        COMMETHOD([],'Activate','iid'),'dwClsCtx'),'pActivationParans'),POINTER(POINTER(IAudioEndpointVolume)),'ppInterface')
        ),'OpenPropertyStore','GetId','GetState',[])
    ]
    pass

class IMMDeviceEnumerator(comtypes.IUnknown):
    _iid_ = GUID('{A95664D2-9614-4F35-A746-DE8DB63617E6}')

    _methods_ = [
        COMMETHOD([],'EnumAudioEndpoints','dataFlow'),'dwStateMask'),POINTER(POINTER(IMMDeviceCollection)),'ppDevices')
        ),'GetDefaultAudioEndpoint','role'),POINTER(POINTER(IMMDevice)),'ppDevices')
        )
    ]





enumerator = comtypes.CoCreateInstance( 
    CLSID_MMDeviceEnumerator,IMMDeviceEnumerator,comtypes.CLSCTX_INPROC_SERVER
)

print enumerator
endpoint = enumerator.GetDefaultAudioEndpoint( 0,1 )
print endpoint
volume = endpoint.Activate( IID_IAudioEndpointVolume,comtypes.CLSCTX_INPROC_SERVER,None )
print volume
print volume.GetMasterVolumeLevel()
print volume.GetVolumeRange()
#volume.SetMasterVolumeLevel(-65,None) uncomment for 0 volume
#volume.SetMasterVolumeLevel(-1,None) uncomment for full volume
volume.SetMasterVolumeLevel(-25,None) #Change the first argument for controlling the volume remember it should be -ve not less than -65