QueryFilter pQueryFilter = new QueryFilter();

String whereclause = "UPPER(/"NAME/") like UPPER('%jack%')";

pQueryFilter.setWhereClause(whereclause);

在条件语句上的前后都加上UPPER转换，这样就不区分大小写了。

以下有VB的IQueryFilter.WhereClause Property文档：

http://edndoc.esri.com/arcobjects/9.2/ComponentHelp/esrigeodatabase/IQueryFilter_WhereClause.htm

Selecting features and graphics

http://webhelp.esri.com/arcgisdesktop/9.2/index.cfm?TopicName=SQL_reference