Dim fd As OpenFileDialog = New OpenFileDialog() 
Dim strFileName As String

fd.Title = "Open File Dialog"
fd.InitialDirectory = "C:\"
fd.Filter = "All files (*.*)|*.*|All files (*.*)|*.*"
fd.FilterIndex = 2
fd.RestoreDirectory = True

If fd.ShowDialog() = DialogResult.OK Then
   strFileName = fd.FileName
End If

然后，您可以使用File类。