JS：

$(document).ready(function () {
    $(".attachmentUpload").kendoUpload({
        async: {
            saveUrl: "SaveAttachment.aspx",autoUpload: true
        }
    });
});

页：

<input name="attachmentUpload" id="attachmentUpload" type="file" class="attachmentUpload" />

SaveAttachment.aspx.cs

public partial class SaveAttachment : Page
{
    protected void Page_Load(object sender,EventArgs e)
    {
        Response.Expires = -1;
        try
        {
            HttpPostedFile postedFile = Request.Files["attachmentUpload"];
            //do something with your postedfile
            Response.ContentType = "application/json";
            Response.Write("{}");
        }
        catch (Exception ex)
        {
            Response.Write(ex.ToString());

        }
    }
}

SaveAttachment.aspx：

<%@ Page Language="C#" CodeBehind="SaveAttachment.aspx.cs" Inherits="Nstar.WebUI.Pages.SaveAttachment" EnableTheming="false" StyleSheetTheme="" Theme="" %>