基于Android Documentation：

public void setLineSpacing (float add,float mult)

Each line will have its height multiplied by mult and have add added to it.

所以这是你可以选择做的：

myTextView.setLineSpacing(TypedValue.applyDimension(TypedValue.COMPLEX_UNIT_DIP,5.0f,getResources().getDisplayMetrics()),1.0f);

或者你可以修改android：lineSpacingExtra的XML Layout. (见Android Documentation.)

<TextView
    android:id="@+id/txtview"
    android:layout_height="wrap_content"
    android:layout_width="fill_parent"
    android:lineSpacingExtra="5dp" />